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Endothelial dysfunction, characterized by diminished endothelial progenitor cell ( EPC ) function and flow-mediated vasodilation ( FMD ), is a clinically significant feature of heart failure ( HF ). ...


Whether culture-expanded mesenchymal stem cells or whole bone marrow mononuclear cells are safe and effective in chronic ischemic cardiomyopathy is controversial. The aim of TAC-HFT trial was to de ...


ViaCyte, a regenerative medicine company developing a cell replacement therapy for the treatment of diabetes, has announced that it has filed an Investigational New Drug application ( IND ) with the U ...


Researchers at Gladstone Institutes have developed a technique in animal models that could replenish the very cells destroyed by the disease. The team's findings, published in the journal Cell Stem Ce ...


Rheumatoid arthritis is the most common inflammatory arthritis, affecting 0.5% to 1% of the general population worldwide.The current pharmacological management of rheumatoid arthritis relies on interv ...


The aim of the study was to investigate the therapeutic potential of iPSC- derived neural stem cells ( NSCs ) transplantation in an animal model of amyotrophic lateral sclerosis ( ALS ).Amyotrophic la ...


The Food and Drug Administration ( FDA ) has approved the California Stem Cell’s application to begin a phase III clinical trial exploring the potential of a cancer stem cell-based platform therapy to ...


Advanced melanoma patients who received an experimental patient-specific tumor stem cell therapy as part of several clinical trials experienced superior survival rates compared to patients who did not ...


Researchers at UCLA's Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research have successfully established the foundation for using hematopoietic stem cells from the bone marrow o ...


Harvard Stem Cell researchers have discovered that the same chemicals that stimulate muscle development in zebrafish can also be used to differentiate human stem cells into muscle cells in the laborat ...


The first randomized, placebo-controlled U.S. clinical trial to assess the use of bone marrow-derived mononuclear cells ( BMC ) in patients after a ST-elevation myocardial infarction ( STEMI ) demonst ...


A study for the treatment of heart failure after myocardial infarction found that the extract derived from bone marrow cells is as effective as therapy using bone marrow stem cells for improving cardi ...


A case report published in the journal, PLoS Medicine, describes a rare side effect of human fetal stem cell therapy. Ninette Amariglio and Gideon Rechavi from the Sheba Medical Center, Tel Aviv, Is ...


A study has shown that it is possible to use human embryonic stem-cells ( hESCs ) to produce temporary skin substitutes for patients awaiting skin grafts after, for example, serious burn injuries. ...


A single organ may contain more than one type of adult stem cell, a discovery that complicates prospects for using the versatile cells to replace damaged tissue as a treatment for disease. In the j ...